| Date | Home team | Away team | Venue | ||
|---|---|---|---|---|---|
| 10:59am Wed 25 Apr | Essendon (79) | lost to | Collingwood (95) | Melbourne Cricket Ground | |
| First game of the round is worth 2 points! | |||||
| 10:59am Wed 25 Apr | Port Adelaide (96) | defeated | St. Kilda (43) | AAMI Stadium | |
| 10:59am Wed 25 Apr | Richmond (76) | lost to | West Coast Eagles (99) | Melbourne Cricket Ground | |
| 10:59am Wed 25 Apr | Sydney (109) | defeated | Melbourne (60) | Sydney Cricket Ground | |
| 10:59am Wed 25 Apr | Carlton (124) | lost to | Brisbane Lions (136) | Telstra Dome | |
| 10:59am Wed 25 Apr | Hawthorn (93) | lost to | Western Bulldogs (110) | Melbourne Cricket Ground | |
| 10:59am Wed 25 Apr | Geelong (102) | lost to | Kangaroos (118) | Skilled Stadium | |
| 10:59am Wed 25 Apr | Fremantle (58) | defeated | Adelaide (57) | Subiaco | |
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