| Date | Home team | Away team | Venue | ||
|---|---|---|---|---|---|
| 5:00pm Fri 4 May | St. Kilda (125) | defeated | Carlton (82) | Telstra Dome | |
| First game of the round is worth 2 points! | |||||
| 5:00pm Fri 4 May | Essendon (96) | lost to | Hawthorn (131) | Melbourne Cricket Ground | |
| 5:00pm Fri 4 May | West Coast Eagles (77) | defeated | Western Bulldogs (62) | Subiaco | |
| 5:00pm Fri 4 May | Kangaroos (111) | defeated | Sydney (95) | Telstra Dome | |
| 5:00pm Fri 4 May | Adelaide (62) | lost to | Collingwood (86) | AAMI Stadium | |
| 5:00pm Fri 4 May | Brisbane Lions (720) | defeated | Fremantle (75) | Gabba | |
| 5:00pm Fri 4 May | Melbourne (71) | lost to | Port Adelaide (76) | Melbourne Cricket Ground | |
| 5:00pm Fri 4 May | Richmond (65) | lost to | Geelong (222) | Telstra Dome | |
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